noise: Estimation of Intrinsic and Extrinsic Noise from Single-Cell Data

Functions to calculate estimates of intrinsic and extrinsic noise from the two-reporter single-cell experiment, as in Elowitz, M. B., A. J. Levine, E. D. Siggia, and P. S. Swain (2002) Stochastic gene expression in a single cell. Science, 297, 1183-1186. Functions implement multiple estimators developed for unbiasedness or min Mean Squared Error (MSE) in Fu, A. Q. and Pachter, L. (2016). Estimating intrinsic and extrinsic noise from single-cell gene expression measurements. Statistical Applications in Genetics and Molecular Biology, 15(6), 447-471.

Version: 1.0.2
Depends: R (≥ 2.10)
Imports: preprocessCore
Published: 2024-02-29
DOI: 10.32614/CRAN.package.noise
Author: Audrey Qiuyan Fu and Lior Pachter
Maintainer: Audrey Q. Fu <audreyqyfu at>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: no
CRAN checks: noise results


Reference manual: noise.pdf


Package source: noise_1.0.2.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): noise_1.0.2.tgz, r-oldrel (arm64): noise_1.0.2.tgz, r-release (x86_64): noise_1.0.2.tgz, r-oldrel (x86_64): noise_1.0.2.tgz
Old sources: noise archive


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