dinamic: A Method to Analyze Recurrent DNA Copy Number Aberrations in Tumors

In tumor tissue, underlying genomic instability can lead to DNA copy number alterations, e.g., copy number gains or losses. Sporadic copy number alterations occur randomly throughout the genome, whereas recurrent alterations are observed in the same genomic region across multiple independent samples, perhaps because they provide a selective growth advantage. This package implements the DiNAMIC procedure for assessing the statistical significance of recurrent DNA copy number aberrations (Bioinformatics (2011) 27(5) 678 - 685).

Version: 1.0.1
Depends: R (≥ 4.2.0)
Suggests: R.rsp
Published: 2024-03-15
DOI: 10.32614/CRAN.package.dinamic
Author: Vonn Walter ORCID iD [aut, cre], Andrew B. Nobel [aut], Fred A. Wright [aut]
Maintainer: Vonn Walter <vwalter1 at pennstatehealth.psu.edu>
License: GPL-3
NeedsCompilation: no
Materials: README NEWS
CRAN checks: dinamic results


Reference manual: dinamic.pdf


Package source: dinamic_1.0.1.tar.gz
Windows binaries: r-devel: dinamic_1.0.1.zip, r-release: dinamic_1.0.1.zip, r-oldrel: dinamic_1.0.1.zip
macOS binaries: r-release (arm64): dinamic_1.0.1.tgz, r-oldrel (arm64): dinamic_1.0.1.tgz, r-release (x86_64): dinamic_1.0.1.tgz, r-oldrel (x86_64): dinamic_1.0.1.tgz
Old sources: dinamic archive

Reverse dependencies:

Reverse imports: DiNAMIC.Duo


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