SimReg: Similarity Regression

Similarity regression, evaluating the probability of association between sets of ontological terms and binary response vector. A no-association model is compared with one in which the log odds of a true response is linked to the semantic similarity between terms and a latent characteristic ontological profile - 'Phenotype Similarity Regression for Identifying the Genetic Determinants of Rare Diseases', Greene et al 2016 <doi:10.1016/j.ajhg.2016.01.008>.

Version: 3.4
Depends: R (≥ 3.0.0)
Imports: Rcpp (≥ 0.11.1), ontologyIndex (≥ 2.0), ontologySimilarity (≥ 2.0), ontologyPlot
LinkingTo: Rcpp
Suggests: knitr, rmarkdown
Published: 2024-02-21
DOI: 10.32614/CRAN.package.SimReg
Author: Daniel Greene
Maintainer: Daniel Greene <dg333 at>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: yes
CRAN checks: SimReg results


Reference manual: SimReg.pdf
Vignettes: Similarity Regression - Introduction
Prior phenotypic information


Package source: SimReg_3.4.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): SimReg_3.4.tgz, r-oldrel (arm64): SimReg_3.4.tgz, r-release (x86_64): SimReg_3.4.tgz, r-oldrel (x86_64): SimReg_3.4.tgz
Old sources: SimReg archive


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