BioPETsurv: Biomarker Prognostic Enrichment Tool for Time-to-Event Trial

Prognostic Enrichment is a strategy of enriching a clinical trial for testing an intervention intended to prevent or delay an unwanted clinical event. A prognostically enriched trial enrolls only patients who are more likely to experience the unwanted clinical event than the broader patient population (R. Temple (2010) <doi:10.1038/clpt.2010.233>). By testing the intervention in an enriched study population, the trial may be adequately powered with a smaller sample size, which can have both practical and ethical advantages. This package provides tools to evaluate biomarkers for prognostic enrichment of clinical trials with survival/time-to-event outcomes.

Version: 0.1.0
Depends: R (≥ 3.1.0)
Imports: survival, ggplot2, gridExtra
Published: 2020-01-12
DOI: 10.32614/CRAN.package.BioPETsurv
Author: Si Cheng [cre, aut], Kathleen F. Kerr [ctb]
Maintainer: Si Cheng <chengsi at>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: no
CRAN checks: BioPETsurv results


Reference manual: BioPETsurv.pdf


Package source: BioPETsurv_0.1.0.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): BioPETsurv_0.1.0.tgz, r-oldrel (arm64): BioPETsurv_0.1.0.tgz, r-release (x86_64): BioPETsurv_0.1.0.tgz, r-oldrel (x86_64): BioPETsurv_0.1.0.tgz


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