Evaluate or optimize designs for nonlinear mixed effects models using the Fisher Information matrix. Methods used in the package refer to Mentré F, Mallet A, Baccar D (1997) <doi:10.1093/biomet/84.2.429>, Retout S, Comets E, Samson A, Mentré F (2007) <doi:10.1002/sim.2910>, Bazzoli C, Retout S, Mentré F (2009) <doi:10.1002/sim.3573>, Le Nagard H, Chao L, Tenaillon O (2011) <doi:10.1186/1471-2148-11-326>, Combes FP, Retout S, Frey N, Mentré F (2013) <doi:10.1007/s11095-013-1079-3> and Seurat J, Tang Y, Mentré F, Nguyen TT (2021) <doi:10.1016/j.cmpb.2021.106126>.
Version: | 6.0.3 |
Depends: | R (≥ 4.0.0) |
Imports: | inline, utils, methods, deSolve, Deriv, scales, devtools, ggplot2, Matrix, pracma, stringr, Rcpp, knitr, rmarkdown, kableExtra |
Published: | 2024-03-23 |
DOI: | 10.32614/CRAN.package.PFIM |
Author: | France Mentré [aut], Romain Leroux [aut, cre], Jérémy Seurat [aut], Lucie Fayette [aut], Emmanuelle Comets [ctb], Sylvie Retout [ctb] |
Maintainer: | Romain Leroux <romain.leroux at inserm.fr> |
License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
URL: | http://www.pfim.biostat.fr/ |
NeedsCompilation: | no |
CRAN checks: | PFIM results |
Reference manual: | PFIM.pdf |
Vignettes: |
Design evaluation and optimization in discrete space Design evaluation and optimization in continuous space Library of models |
Package source: | PFIM_6.0.3.tar.gz |
Windows binaries: | r-devel: PFIM_6.0.3.zip, r-release: PFIM_6.0.3.zip, r-oldrel: PFIM_6.0.3.zip |
macOS binaries: | r-release (arm64): PFIM_6.0.3.tgz, r-oldrel (arm64): PFIM_6.0.3.tgz, r-release (x86_64): PFIM_6.0.3.tgz, r-oldrel (x86_64): PFIM_6.0.3.tgz |
Old sources: | PFIM archive |
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