MARVEL: Revealing Splicing Dynamics at Single-Cell Resolution

Alternative splicing represents an additional and underappreciated layer of complexity underlying gene expression profiles. Nevertheless, there remains hitherto a paucity of software to investigate splicing dynamics at single-cell resolution. 'MARVEL' enables splicing analysis of single-cell RNA-sequencing data generated from plate- and droplet-based library preparation methods.

Version: 1.4.0
Depends: R (≥ 3.5.0)
Imports: ggplot2 (≥ 3.3.2), Matrix (≥ 1.3-3), methods, plyr (≥ 1.8.4), scales (≥ 1.1.1)
Suggests: AnnotationDbi (≥ 1.48.0), Biostrings (≥ 2.56.0), BSgenome (≥ 1.56.0), BSgenome.Hsapiens.NCBI.GRCh38 (≥ 1.3.1000), clusterProfiler (≥ 3.16.0), factoextra (≥ 1.0.7), FactoMineR (≥ 2.3), fitdistrplus (≥ 1.1-1), GenomicRanges (≥ 1.42.0), ggnewscale (≥ 0.4.5), ggrepel (≥ 0.9.1), gridExtra (≥ 2.3), gtools (≥ 3.9.2), IRanges (≥ 2.24.1), kableExtra (≥ 1.3.1), knitr (≥ 1.29), kSamples (≥ 1.2-9), markdown (≥ 1.1), MAST (≥ 1.16.0), org.Hs.eg.db (≥ 3.10.0), org.Mm.eg.db (≥ 3.11.4), parallel, pheatmap (≥ 1.0.12), reshape2 (≥ 1.4.4), rmarkdown (≥ 2.3), S4Vectors (≥ 0.26.1), stringr (≥ 1.4.0), textclean (≥ 0.9.3), twosamples (≥ 1.1.1), wiggleplotr (≥ 1.12.1)
Published: 2022-10-31
DOI: NA
Author: Sean Wen [aut, cre]
Maintainer: Sean Wen <sean.wenwx at gmail.com>
License: GPL-3
NeedsCompilation: no
CRAN checks: MARVEL results

Documentation:

Reference manual: MARVEL.pdf
Vignettes: MARVEL

Downloads:

Package source: MARVEL_1.4.0.tar.gz
Windows binaries: r-devel: MARVEL_1.4.0.zip, r-release: MARVEL_1.4.0.zip, r-oldrel: MARVEL_1.4.0.zip
macOS binaries: r-release (arm64): MARVEL_1.4.0.tgz, r-oldrel (arm64): MARVEL_1.4.0.tgz, r-release (x86_64): MARVEL_1.4.0.tgz, r-oldrel (x86_64): MARVEL_1.4.0.tgz
Old sources: MARVEL archive

Linking:

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